Vol. 23 No. 3 (2026)
Medic Nutricia : Jurnal Ilmu Kesehatan, ISSN : 3025-8855

Articles

REVIEW ARTIKEL: FORMULASI DAN EVALUASI TABLET EFFERVESCENT EKSTRAK JAHE (Zingiber officinale)

DOI: https://doi.org/10.2238/yhvkpd81

Published 2026-07-03

  • Iqbal Pahdulrahman
    • ,
  • Yahdini Nurhasanah
    • ,
  • Silfi Nur Aini
    • ,
  • Echa Salsabila
    • ,
  • Helsi Tiara Plani
    • ,
  • Alif Ramadhan
    • ,
  • Hilwa Dwi Darma
    • ,
  • Fauziah Rahma Indah Sari
    • ,
  • Salsanabila
    • ,
  • Mutiara Lubis
    • ,
  • Nasyatul Aulia Fitri

Iqbal Pahdulrahman
Universitas Muhammadiyah Riau

Yahdini Nurhasanah
Universitas Muhammadiyah Riau

Silfi Nur Aini
Universitas Muhammadiyah Riau

Echa Salsabila
Universitas Muhammadiyah Riau

Helsi Tiara Plani
Universitas Muhammadiyah Riau

Alif Ramadhan
Universitas Muhammadiyah Riau

Hilwa Dwi Darma
Universitas Muhammadiyah Riau

Fauziah Rahma Indah Sari
Universitas Muhammadiyah Riau

Salsanabila
Universitas Muhammadiyah Riau

Mutiara Lubis
Universitas Muhammadiyah Riau

Nasyatul Aulia Fitri
Universitas Muhammadiyah Riau

Abstract

Tablet effervescent merupakan salah satu bentuk sediaan farmasi yang semakin banyak dikembangkan karena memiliki keunggulan berupa waktu larut yang cepat, kemudahan penggunaan, peningkatan kenyamanan pasien, serta kemampuan meningkatkan stabilitas dan penerimaan terhadap bahan aktif herbal. Jahe (Zingiber officinale) merupakan tanaman obat yang kaya akan senyawa bioaktif, seperti gingerol, shogaol, zingeron, flavonoid, dan senyawa fenolik, yang memiliki aktivitas antioksidan, antiinflamasi, antimikroba, dan antiemetik. Artikel ini bertujuan untuk mengulas berbagai penelitian mengenai formulasi dan evaluasi tablet effervescent ekstrak jahe serta faktor-faktor yang memengaruhi mutu sediaan. Metode yang digunakan adalah literature review dengan mengkaji 25 artikel ilmiah nasional dan internasional yang diterbitkan pada periode 2021-2026. Hasil kajian menunjukkan bahwa keberhasilan formulasi tablet effervescent dipengaruhi oleh pemilihan bahan aktif, keseimbangan komposisi asam sitrat, asam tartrat, dan natrium bikarbonat, serta penggunaan bahan pengikat dan bahan tambahan lainnya. Evaluasi mutu yang umum dilakukan meliputi organoleptik, keseragaman bobot, kekerasan, friabilitas, kadar air, waktu larut, pH, dan stabilitas. Penelitian melaporkan bahwa formulasi tablet effervescent ekstrak jahe memenuhi persyaratan mutu fisik dengan waktu larut yang cepat, kadar air rendah, kekerasan dan friabilitas sesuai standar, serta mampu mempertahankan aktivitas antioksidan dan sifat fungsional ekstrak jahe.

Keywords

Zingiber officinale, tablet effervescent, formulasi, evaluasi, jahe, literature review

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References

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